Melanocortin-4 receptor gene and physical activity in the Québec Family Study
نویسندگان
چکیده
منابع مشابه
Association between the Melanocortin-4 Receptor (MC4R) Gene Polymorphisms and Growth Trait in Sumba Ongole Cattle
Melanocortin-4 receptor (MC4R) gene has been known as a candidate gene for growth traits in livestock. This research was aimed to identify the polymorphism of MC4R gene and its association with growth traits in Sumba Ongole (SO) cattle. The growth traits data consist of body weight and body size. Eighty four blood samples were collected and used for DNA isolation. The...
متن کاملRapid communication: linkage and physical mapping of the porcine melanocortin-4 receptor (MC4R) gene.
Genus and Species. Sus scrofa. Locus. Pig Melanocortin-4 Receptor (MC4R) gene. Source and Description of Primers. Primers were designed from well-conserved sequence regions between the human and rat MC4R genes (Genbank accession no. S77415 and U67863, respectively). The primers were used to amplify approximately 760 bp of the porcine MC4R gene from genomic DNA. The sequence of the PCR product s...
متن کاملPhysical Activity, Energy Expenditure, and Defense of Body Weight in Melanocortin 4 Receptor-Deficient Male Rats
Melanocortin 4 receptor (MC4R) variants contribute to human obesity, and rats lacking functional MC4R (Mc4rK314X/K314X) are obese. We investigated the hypothesis that low energy expenditure (EE) and physical activity contribute to this obese phenotype in male rats, and determined whether lack of functional MC4R conferred protection from weight loss during 50% calorie restriction. Though Mc4rK31...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولMelanocortin-4 receptor gene mutations in obese Slovak children.
The most common etiology of non-syndromic monogenic obesity are mutations in gene for the Melanocortin-4 receptor (MC485) with variable prevalence in different countries (1.2-6.3 % of obese children). The aim of our study was 1) to search for MC4R mutations in obese children in Slovakia and compare their prevalence with other European countries, and 2) to describe the phenotype of the mutation ...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2004
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0802869